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AI Unpacks Generational Stereotypes, Highlighting Key Differences, but Beer Bridges the Gap

AIport

What happens when you ask generative AI models to depict Baby Boomers, Gen X, Millennials, and Gen Z? You might expect tech-challenged Boomers and avocado-loving Millennials. But what you get is far more interesting and in some cases, unexpected. A joint research project conducted by AIport and Turing Post last month analyzed over 1200 AI-generated images across four different models—Stable Diffusion, Midjourney, YandexART, and ERNIE-ViLG. The findings have revealed both familiar stereotypes and surprising quirks about how AI perceives these generations. Sad Boomers, Happy Zoomers? Contrary to the carefree Boomer stereotype, AI models like Midjourney depict Baby Boomers as introspective, or even somber, often bundled up and gazing wistfully into the distance—a reflection, perhaps, of their disillusionment with the unfulfilled ideals of the 1960s cultural revolution. However, the ERNIE-ViLG model, likely trained on datasets with a more collectivist cultural slant, shows 93% of Boomers smiling. This fascinating contrast underscores the cultural differences embedded in different AI models. Meanwhile, Gen Z’s images are vibrant and diverse, reflecting their reputation as a generation that embraces individuality, inclusivity, and self-expression. The AI-generated images depict Zoomers in colorful, highly detailed scenarios, making them the most visually distinct generation in the study. Generations Through the AI Lens The research explored how generations are portrayed in five key aspects of life: identity, relationships, work, lifestyle, and consumer habits. The AI models revealed consistent patterns and stereotypes; for example, males predominated in the depictions of Boomers and Gen Xers across all four models, while many images of Millennials and Zoomers showed greater diversity and more female representation. Surprisingly, Gen X appears to be the least well-understood generation by AI, characterized by fewer defining features compared to all other generations, likely due to the limited amount of training data available. The one stereotypical Gen X leitmotif that AI consistently identifies is their fondness for flannel shirts—an unmistakable symbol of the 1990s grunge scene worn by Gen Xers who were rebellious teenagers and young adults during that era. As for one (un)expected commonality… It’s beer. Whether they’re Millennials job-hopping or Boomers reminiscing about the good old days, AI consistently showed beer in 34% of the produced images across all generations. Prompt Engineering and AI Insights The prompts for this research were carefully crafted to avoid bias, using neutral phrases like "A Millennial at work" or "A Boomer relaxing." The results offer a telling look at how generative AI models mirror societal stereotypes, often shaped by the data they're trained on. These findings open the door to deeper discussions on how AI reflects, and sometimes distorts, cultural narratives. "Whether we think we can learn about generations from these images depends upon how confident we feel that the training data that went in is an accurate image of the self identity of a group,” explains Senior Engineer and Sociologist Stephanie Kirmer, who analyzed the findings. “For the younger sets, I don’t think we can know how much of it is media representation created by people outside the group versus how much is selfie-style personal expression. Some of what we’re getting, especially for the older groups who don’t contribute as much self-generated visual media online, is perceptions of that group from advertising and media, which we know has inherent flaws." About the Study The study examined the outputs of four globally recognized generative AI models, each with distinct aesthetic and cultural nuances, providing a comprehensive look at how each generation is portrayed visually. The selected models included Stable Diffusion, Midjourney, YandexART, and ERNIE-ViLG, offering diverse perspectives from different regions across the globe. Conclusion Whether confirming or contradicting societal stereotypes, AI-generated images provide a fascinating snapshot of how technology interprets generational differences. The fact that beer remains a unifying theme across all four models shows that, no matter our age, some things—like enjoying a cold one—transcend generational divides. To learn more about the project, visit https://www.aigenerations.tech/. Hero images for the media: Google Drive Link About AIport AIport is an emerging community of AI/ML enthusiasts and practitioners with a goal of providing a truly global view of the AI/ML/DS landscape. https://www.blog.aiport.tech/ About Turing Post Turing Post is everything you need to make smarter decisions about AI. https://www.turingpost.com/ Contact Details Nick Leighton nick.leighton@nettresultsllc.com Company Website https://www.aigenerations.tech/

September 23, 2024 10:00 AM Eastern Daylight Time

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Siti Non AAMS - Migliori Siti Casino & Scommesse 2024

AM Europe

Sono sempre di più gli utenti italiani che scelgono di scommettere sui cosiddetti siti non AAMS. Questi concessionari operano con licenze internazionali e garanwtiscono l’accesso a generosi bonus senza deposito, a più metodi di pagamento, e a dei giochi che sui siti AAMS solitamente non si trovano. Chiunque sia alla ricerca di siti di scommesse legali in Italia seppur al di fuori della normativa AAMS, in questa guida andremo proprio a fornire una panoramica sui migliori operatori di questo genere. Tabe di Siti Non AAMS & Casino non AAMS Perché gli Italiani Scelgono i Bookmaker Non AAMS Gli italiani scelgono i siti non AAMS per tante motivazioni differenti, che si rifanno principalmente a ciò che riguarda le promozioni, alla selezione di giochi e prodotti disponibili e alla struttura di diverse funzionalità delle piattaforme stesse. Bonus più generosi Meno restrizioni Ampia varietà giochi Programmi VIP esclusivi Tornei giornalieri Lista dei Migliori Siti non AAMS Panoramica Di seguito, proponiamo una lista di quelli che a nostro parere sono i migliori siti non AAMS, con tanto di descrizione dei punti di forza di ciascuno: HappySlots: Questo casinò rappresenta il paradiso per gli amanti delle slot machine, in quanto propone una selezione capace di abbracciare migliaia di titoli differenti. I giocatori possono quindi esplorare una miriade di temi e funzionalità all’interno di HappySlots, portale capace di far provare sempre qualcosa di nuovo ai propri utenti, soprattutto grazie alle frequenti aggiunte di titoli originali. WildTokyo: Perfetto per chi cerca dell’adrenalina su base quotidiana, questo casinò online si ditingue per offrire promozioni e gare con premi che vengono assegnati ogni giorno; infatti, all’interno di questo portale vengono proposte giornalmente nuove sfide e bonus che rendono l’esperienza di gioco sempre dinamica e ricca di opportunità da cogliere per usufruire di ricompense extra. ProntoBet: Con un palinsesto sportivo che non ha nulla da invidiare ai principali bookies mondiali, ProntoBet è sicuramente il sito ideale per gli appassionati di scommesse sportive. L’offerta di ProntoBet copre tutti gli eventi sportivi globali e consente agli utenti di scommettere su una vasta gamma di discipline con quote molto competitive. Winsane: Questo portale è rinomato per il suo eccellente e ben strutturato programma fedeltà; grazie a quest’ultimo, i giocatori più assidui possono beneficiare di bonus esclusivi e trattamenti VIP personalizzati che vanno a premiare la loro fedeltà con vantaggi unici e premi assegnati su misura. Cashwin: Con un’offerta che prevede la fruizione costante di nuove promozioni per nuovi iscritti e utenti già registrati, Cashwin è senza dubbio l’ideale per chi ama passare il proprio tempo nel tentativo di sfruttare al meglio dei bonus vantaggiosi. Le promozioni disponibili sono generose e spesso sono pensate per incrementare percentualmente i fondi di gioco che vengono depositati in maniera davvero significativa. Quickwin: La punta di diamante di Quickwin è costituita dalla lounge dedicata al casinò live, in cui è possibile trovare tutti i giochi con croupier dal vivo. Gli amanti dell’interattività e della dinamicità del casinò potranno trovare un’ampia selezione di titoli in grado di ricreare fedelmente l’ambiente di un casinò reale, soprattutto grazie alla qualità dei giochi offerti. Perchè gli Italiani scelgono i Siti non AAMS Come detto in precedenza, i siti non AAMS stanno rapidamente guadagnando popolarità tra gli scommettitori italiani, poiché offrono una serie di vantaggi che superano quelli dei bookmaker regolamentati dall’AAMS. Grazie a bonus mediamente più generosi, metodi di pagamento che includono anche le criptovalute e selezioni di giochi più estese, questi siti stanno diventando sempre più gettonati. Qui sotto abbiamo preparato un elenco di motivi, dettagliati uno per uno, per i quali gli utenti si stanno spostando sempre più verso queste alternative ai casinò online tradizionali. Bonus e promozioni: I siti non AAMS propongono bonus più generosi rispetto alle controparti regolate dall’AAMS e spesso assicurano anche giri gratuiti e bonus senza deposito che sono sempre molto graditi a tutti gli utenti; Metodi di pagamento: I siti non AAMS supportano molti altri metodi di pagamento come le criptovalute oltre alle opzioni più classiche come possono essere le carte di credito e i portafogli elettronici; Selezione di giochi: Offrendo una gamma di giochi da casinò tendenzialmente più ampia rispetto ai casinò normali, i siti non AAMS si fanno preferire per la maggiore varietà a cui gli utenti possono avere accesso; Licenze e sicurezza: Pur non regolamentati dall'AAMS, i siti non AAMS possiedono licenze internazionali, assicurando elevati standard di sicurezza e protezione per dati personali e transazioni finanziarie. Supporto clienti: Il supporto multilingue dei siti non AAMS, solitamente disponibile tramite chat live, email e telefono, garantisce assistenza immediata che permette di risolvere ogni tipologia di problema efficientemente. Pro e Contro dei Siti Non AAMS Pro: Ampia gamma di bonus, varietà di giochi, flessibilità nei pagamenti e meno restrizioni. Contro: Il servizio clienti di queste piattaforme a volte potrebbe tardare più del dovuto nelle risposte. Cos'è un sito di scommesse sportive non AAMS? Un sito di scommesse sportive non AAMS è una piattaforma che opera senza la licenza italiana rilasciata dall’Agenzia delle Dogane e dei Monopoli, ma che possiede comunque una attestazione internazionale. Questi siti consentono agli utenti di piazzare scommesse sempre sulla maggioranza degli eventi sportivi internazionali, ma offrendo un numero di mercati che generalmente va oltre a quello proposto dai siti AAMS; infatti, come abbiamo già sottolineato, le piattaforme non AAMS sono note per avere regole meno rigide sotto tutti i punti di vista, il che significa spesso limiti di scommessa più alti, bonus più generosi e metodi di pagamento più variegati. Come registrarsi nei Siti non AAMS Registrarsi su un sito di scommesse non AAMS spesso passa da un processo più rapido rispetto a quello che si deve affrontare all’interno dei casinò tradizionali, grazie a procedure meno rigide in termini di raccolta dati. In molti casi, i siti non AAMS consentono di registrarsi con metodi alternativi come Google o Apple ID, in modo da abbattere le tempistiche necessarie per creare un nuovo conto di gioco. Inoltre, al posto della classica procedura di convalida obbligatoria dei documenti entro 30 giorni, come richiesto dai casinò AAMS per evitare la sospensione del conto, i siti non AAMS adottano procedure di Know Your Customer (KYC) meno invasive; questo significa che, anche se il processo di KYC non viene portato a termine correttamente, l'utente può comunque accedere liberamente a tutte le funzionalità del casinò ad eccezione dei prelievi, che vengono resi disponibili solo dopo aver completato questa procedura. Visitare il sito scelto: La prima cosa da fare è recarsi nella homepage del sito di scommesse non AAMS; Cliccare su "Registrati": Successivamente, bisogna cliccare sul pulsante di registrazione che è solitamente piazzato in alto a destra nella pagina principale del sito; Compilare il modulo: Arrivati qui, toccherà all’inserimento dei propri dati personali, come nome, cognome, indirizzo email e numero di telefono; alcuni siti potrebbero richiedere anche la creazione di un nome utente; Verificare l'account: Infine, bisognerà inviare una copia dei documenti richiesti per la verifica dell'identità, passaggio fondamentale per sbloccare la possibilità di effettuare dei prelievi. Giochi da casinò disponibili I siti non AAMS sono particolarmente indicati per gli amanti dei giochi del casinò, in quanto spesso e volentieri sono presenti decine di alternative per ciascuna delle categorie di giochi principali. Giochi da tavolo I giochi da tavolo includono grandi classici come blackjack e baccarat, con molte varianti alternative utili per adattarsi a diversi stili di gioco. Slot Dalle slot tradizionali alle video slot con grafiche particolareggiate, queste piattaforme offrono anche titoli con jackpot progressivi capaci di portare a vincite significative. Casinò live Il casinò live offre un'esperienza estremamente realistica con un croupier reale e include tsvoli di giochi come roulette, blackjack e poker dal vivo. Blackjack Il blackjack è disponibile sia offline live, permettendo ai giocatori di scegliere se giocare a delle partite automatizzate o in diretta con dei croupier. Roulette Le varie versioni di roulette includono quella europea, quella americana e quella francese, con sempre diverse opzioni di scommessa disponibili sia virtualmente che live. I casinò non AAMS sono legali in Italia? Sì, i siti non AAMS sono legali anche in Italia nonostante operino tramite delle licenze internazionali, come possono essere quelle rilasciate da Malta o Curaçao, piuttosto che con licenze AAMS. Questo significa che, pur non essendo regolamentati direttamente dal governo italiano, questi portali possono comunque offrire servizi di scommessa e gioco d'azzardo ai residenti in Italia senza alcuna implicazione a livello legale. Per chiudere, pensiamo sia importante ricordare che, nonostante sia sempre garantito che questi casinò operano legalmente, i giocatori dovrebbero sempre verificare la licenza sotto cui il sito opera per assicurarsi che siano protetti e che i loro fondi siano al sicuro. Metodi di deposito e prelievo Spesso, i siti di scommesse non AAMS danno la possibilità agli utenti di prelevare e versare denaro tramite decine di metodi di pagamenti differenti da quelli solitamente messi a disposizione dai concessionari. Queste piattaforme sono ben consapevoli dell'importanza di effettuare transazioni rapide e sicure, e per questo motivo mettono a disposizione diverse opzioni per soddisfare le esigenze di un pubblico internazionale; che si tratti di carte di credito, portafogli elettronici o bonifici bancari, ogni giocatore può trovare il metodo di pagamento che meglio si adatta alle proprie preferenze e necessità. L'inclusione delle criptovalute in alcuni di questi siti rappresenta un ulteriore passo avanti verso la modernizzazione delle operazioni finanziarie, in modo da garantire non solo velocità, ma anche un alto livello di anonimato e sicurezza. Vediamo ora nel dettaglio quali sono le opzioni di pagamento più comuni disponibili sui siti di scommesse non AAMS. Visa: La carte di credito Visa costituiscono uno dei metodi di pagamento più popolari e diffusi nei siti di scommesse AAMS e non. Visa garantisce che le transazioni siano sempre protette da tecnologie avanzate di crittografia, in modo da ridurre al minimo il rischio di frodi. Inoltre, la velocità delle operazioni consente ai giocatori di avere i fondi disponibili immediatamente per scommettere; tuttavia, è bene ricordare che per alcuni siti potrebbero essere applicate commissioni e che i tempi di prelievo potrebbero variare sulla base delle condizioni imposte dal concessionario. Mastercard: Mastercard è un'altra carta di credito largamente accettata all’interno dei siti non AAMS. Anche questa opzione prevede la stessa rapidità nelle transazioni e la protezione dalle frodi grazie all’utilizzo di sistemi di sicurezza piuttosto avanzati; come per Visa, anche con Mastercard si possono incontrare tempi di attesa per i prelievi che variano a seconda del sito, ma la trasparenza delle commissioni e la velocità nelle operazioni hanno reso questo metodo una scelta molto popolare; Paypal: Paypal è uno dei portafogli elettronici più utilizzati nei siti non AAMS e non. La sua popolarità deriva dalla facilità d'uso della sua interfaccia e dalla velocità di evasione delle transazioni, i cui processi permettono ai giocatori di effettuare depositi e prelievi in pochi click e secondi. Inoltre, ricordiamo che Paypal è sinonimo di un ulteriore livello di sicurezza, in quanto funge da intermediario tra il conto bancario del giocatore e il sito senza che le informazioni sensibili vengano mai condivise direttamente con il casinò. Neteller: Neteller è uno dei portafogli elettronici preferiti dai giocatori che utilizzano i siti non AAMS per via della sua alta velocità e semplicità. Le transazioni con Neteller sono quasi istantanee e permettono di trasferire fondi rapidamente, sia per i depositi che per i prelievi. Inoltre, questo portafoglio elettronico assicura un elevato livello di sicurezza, grazie a sistemi di crittografia avanzati. Bonifico bancario: Operare tramite il bonifico bancario rimane un metodo tradizionale, utilizzato soprattutto da chi preferisce trasferire fondi direttamente dal proprio conto corrente senza l'intermediazione di carte o portafogli elettronici. Anche se questo metodo offre un’elevata sicurezza, grazie al sistema bancario regolamentato, i tempi di elaborazione possono essere più lunghi rispetto ad altre opzioni, richiedendo fino a 5 giorni lavorativi per il completamento di qualsiasi tipo di giocata. Bonus e Promozioni sui Siti non AAMS Uno dei motivi principali per cui molti giocatori scelgono i siti non AAMS sta nella generosità e varietà dei bonus e delle promozioni disponibili. Questi casinò offrono promozioni molto più competitive rispetto ai siti regolamentati dall’AAMS, con cifre spesso superiori, bonus senza deposito, e programmi fedeltà più vantaggiosi. Molti siti non AAMS propongono anche promo come i cashback settimanali o mensili, che permettono di vedersi restituita una percentuale delle perdite subite per via delle giocate non vincenti. Infine, i tornei giornalieri e le race con premi extra sono una caratteristica comune, capace di attirare i giocatori con promozioni dinamiche e costanti. Ecco alcune delle offerte più comuni: Free Spins: Si tratta di gratuiti offerti su slot selezionate, ideali per provare nuovi giochi senza rischiare il proprio denaro. Bonus senza deposito: Uno dei preferiti dai nuovi iscritti, permette di iniziare a giocare senza dover effettuare un deposito con i propri soldi. Wagering: Condizioni di giocata che talvolta sono più favorevoli rispetto ai siti AAMS, consentendo di soddisfare i requisiti di scommessa in modo più semplice. Cashback: Alcuni casinò non AAMS offrono un ritorno percentuale sulle perdite nette, in modo da garantire ai giocatori un piccolo rimborso. Software disponibile sui bookmaker non AAMS I siti non AAMS collaborano con alcuni dei migliori provider di software nel settore del gioco d’azzardo allo scopo di garantire un’esperienza fluida in ogni momento. Questi provider sono responsabili dello sviluppo di giochi equi, con funzionalità innovative e grafiche di alta qualità. Curacao I siti di scommesse con licenza rilasciata dalla giurisdizione di Curacao collaborano con alcuni dei più celebri provider di software della scena, tutto per offrire giochi godibili ed equi. NetEnt Betsoft Evolution Gaming Pragmatic Play Yggdrasil MGA Anche i siti regolati dalla Malta Gaming Authority (MGA) collaborano con fornitori di software leader del settore per assicurare che l’esperienza di gioco sia la migliore possibile. Microgaming Play’n GO Quickspin Thunderkick Evolution Gaming Le Nostre Conclusioni In conclusione, ci siamo convinti del fatto che i siti non AAMS rappresentano senza dubbio un’alternativa valida per chi cerca maggiore libertà, promozioni più generose e un elenco di giochi più fornito rispetto alle disponibilità dei casinò tradizionali. Anche se non regolamentati direttamente dall’AAMS, molti di questi siti operano con licenze riconosciute a livello internazionale che garantiscono inconfutabilmente un livello di sicurezza molto elevato. Tuttavia, ricordiamo che è fondamentale che i giocatori siano consapevoli dei possibili rischi che possono correre e che scelgano piattaforme con una buona reputazione e licenze affidabili come quelle di cui abbiamo parlato all’interno di questa stessa panoramica. Domande Frequenti (FAQ) È sicuro giocare all’interno di un sito non AAMS? Sì, i siti non AAMS che possiedono licenze internazionali come quelle di Curaçao o Malta offrono livelli di sicurezza paragonabili a quelli AAMS. Quali bonus posso ottenere sui siti non AAMS? I siti non AAMS offrono bonus senza deposito, giri gratuiti, cashback e promozioni personalizzate, solitamente in misura maggiore rispetto ai bookmaker AAMS. Posso prelevare le vincite dai siti non AAMS? Sì, i siti non AAMS permettono prelievi tramite carte di credito, portafogli elettronici come Neteller e PayPal, bonifici bancari, criptovalute e non solo. I siti non AAMS sono legali in Italia? Sì, i siti non AAMS sono legali per i giocatori italiani; tuttavia, essendo regolamentati da autorità internazionali, operano al di fuori del sistema di licenze italiano. Contact Details Berardo Bianchi +39 035 0445 9954 Berardo@itsitinonaams.com Company Website https://www.casinolistingonline.com/

September 20, 2024 04:09 AM Eastern Daylight Time

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Industry Update: 3 Exciting Precision Oncology Players to Watch Following Summit’s Meteoric Rise: Silexion, Nuvectis, Scorpian

Global Markets News

Summit Therapeutics (NASDAQ: SMMT) recently captured headlines with the release of its Phase 3 data for ivonescimab, a targeted NSCLC therapy that has generated substantial buzz. The results from its trial conducted in China showed a dramatic 49% reduction in the risk of disease progression or death compared to Merck’s Keytruda, signaling a potentially disruptive force in NSCLC treatment. However, the news wasn’t without its concerns—since the trial data originates from China, there are questions about its applicability to broader, global populations. As noted by BMO Capital Markets’ Evan Seigerman: “Results may or may not be generalizable beyond the China-focused patient population initially assessed.” Despite this, Summit’s valuation has risen by over 100%, now approximating $19 billion. With such a high valuation, the company could see limited room for further significant gains, leading many in the industry to explore other emerging opportunities in precision oncology. Alongside Summit, there are quite a few other players in the field. Some if these companies have even already shown promising initial results and could see similar success in the future if they were to report positive results. These emerging players are worth watching for those interested in following precision oncology drug candidates and pipelines. Among them are precision oncology innovators such as Silexion Therapeutics, Nuvectis Pharma, and Scorpion Therapeutics, which we discuss below. Silexion Therapeutics: Disrupting the KRAS-Driven Cancer Space Silexion Therapeutics (NASDAQ: SLXN) is another under-the-radar player in the precision oncology space, with a focus on KRAS-driven cancers—a notoriously difficult target in oncology. While current small-molecule KRAS inhibitors are making progress, they are often limited to specific mutations, such as KRAS G12C, which accounts for a small percentage of cancers. Silexion’s RNA interference (RNAi) approach offers a broader solution, targeting a wider spectrum of KRAS mutations, particularly in pancreatic cancer, one of the deadliest and most treatment-resistant cancers. At the heart of Silexion’s approach is its LODER™ platform, which delivers siRNA directly to the tumor site, silencing KRAS mutations at the genetic level. This localized delivery not only increases efficacy by concentrating the treatment in the tumor, but it also reduces systemic side effects. Silexion’s next-generation candidate, SIL-204, is an optimized siRNA formulation designed to target pan-KRAS G12x mutations, positioning it to treat a broader range of KRAS-driven cancers beyond pancreatic cancer, such as lung and colorectal cancers. In Phase 2 trials for locally advanced pancreatic cancer, Silexion's LODER™ platform showed a 9.3-month improvement in overall survival when combined with standard chemotherapy. Additionally, the objective response rate (ORR) increased from 20% with chemotherapy alone to 55% with the combination, and in some cases, tumors that were initially non-resectable became operable after treatment with LODER™. These results are especially encouraging given the limited options available for pancreatic cancer patients. SIL-204, is expected to enter Phase 2/3 clinical trials in 2025-2026. What makes Silexion particularly intriguing is its current market valuation. Valued at aproximatly just ~$9 million following its SPAC merger, the company’s valuation could be perceived as low when compared to some of its peers, especially given its innovative technology and promising clinical achievements. Some have wondered whether this low valuation has more to do with dynamics post-SPAC companies. If Silexion can report positive results in its later-stage trials, the company’s outlook could dramatically improve, reflecting the potential of its RNAi-based platform. Like NXP900, SIL-204 could potentially have vast applications across multiple KRAS-driven cancer types, making Silexion a company to watch closely as it advances through clinical development. Nuvectis Pharma: Targeting NSCLC and Beyond by Inhibiting SRC/YES1 Kinases Nuvectis Pharma (NASDAQ: NVCT) has been quietly making strides in the precision oncology sector, developing innovative therapies aimed at overcoming treatment resistance in hard-to-treat cancers. Its lead candidate, NXP900, targets NSCLC by inhibiting the SRC/YES1 kinases, which play critical roles in cancer cell survival and resistance to current therapies. This approach positions NXP900 as a potential game-changer in the treatment of NSCLC, particularly in patients who have developed resistance to EGFR and ALK inhibitors, such as AstraZeneca’s Tagrisso and Novartis’ Alecensa. NXP900 is still in the early stages of clinical development, currently undergoing Phase 1 trials. However, preclinical studies have already shown that it has strong anti-tumor activity in resistant NSCLC models. Even more promising is its potential application beyond NSCLC. Like Summit's ivonescimab, NXP900 focuses on resistance, but it also has broader applications due to its ability to target multiple cancer types driven by SRC/YES1 pathways. This versatility makes it a promising asset not just for NSCLC but also for other difficult-to-treat cancers like squamous cell carcinomas. In addition to NXP900, Nuvectis is advancing NXP800, another precision oncology candidate that is further along in the clinical development process. NXP800 is currently in Phase 1b trials, targeting ARID1a-mutated cancers such as ovarian and endometrial cancers. The early clinical data for NXP800 is promising, showing positive responses in patients with platinum-resistant ovarian cancer. With two strong candidates in the pipeline, Nuvectis is positioning itself as a formidable player in the precision oncology landscape. As Summit’s ivonescimab continues to gain attention, Nuvectis’ earlier-stage NXP900, with its NSCLC focus and beyond, could see similar success in the future if clinical results continue to trend positively. Scorpion Therapeutics: Pioneering Mutant-Selective Therapies Scorpion Therapeutics is redefining the frontier of precision oncology with its focus on delivering highly selective small molecules targeting validated and previously undruggable cancer mutations. Its lead candidate, STX-478, is a mutant-selective, allosteric PI3Kα inhibitor currently in Phase 1/2 trials for advanced solid tumors. Early data presented at the ESMO Congress 2024 highlighted its potential, with STX-478 demonstrating a 23% overall response rate in breast cancer and a 21% response rate across all tumor types, positioning it as a potentially best-in-class PI3Kα inhibitor. STX-478 is notable for its ability to spare wild-type PI3Kα activity in normal tissues, avoiding the toxicities seen with previous PI3Kα inhibitors, such as hyperglycemia and rash. Tumor reductions were seen in 72% of patients treated with STX-478 as a monotherapy, with circulating tumor DNA levels dropping in 86% of patients. This mutant-selective precision could help overcome the limitations of existing PI3Kα inhibitors, which have struggled with dose-limiting toxicities. In July 2024, Scorpion raised $150 million in a Series C financing round, co-led by Frazier Life Sciences and Lightspeed Venture Partners. The additional funding will support the advancement of STX-478 and other pipeline assets, positioning Scorpion for further clinical success. Scorpion’s pipeline includes a broad range of wholly-owned compounds that target both validated and novel cancer targets, positioning the company for future expansion into larger patient populations. As STX-478 progresses through clinical development, Scorpion is poised to become a significant player in the precision oncology space, making it another company worth watching closely. Optimistic Outlook for Precision Oncology The precision oncology space is experiencing a golden era of innovation, with companies like Summit Therapeutics, Nuvectis Pharma, Silexion Therapeutics, and Scorpion Therapeutics leading the charge. As the focus shifts towards targeted therapies that address resistance mechanisms, the market is increasingly favoring companies with novel approaches and broad applications. Summit’s meteoric rise has shown that there is tremendous potential for companies that can demonstrate efficacy in overcoming cancer resistance. While Summit has already captured much of the current attention, companies like Nuvectis, Silexion, and Scorpion, with their earlier-stage pipelines, offer exciting opportunities for the industry to keep a close eye on. As these companies continue to report clinical data and advance through trials, the potential for breakthroughs in treating some of the most difficult cancers grows stronger. With targeted therapies offering the possibility of overcoming resistance without the need for chemotherapy, the future of cancer treatment looks brighter than ever. For those in the oncology space, keeping a close eye on emerging players like Nuvectis, Silexion, and Scorpion could lead to transformative developments as the field of precision oncology continues to evolve. * * * This update may include speculative forward looking statements. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those in the forward-looking statements as a result of various factors. the BioTech and Pharma industries are volatile and risky and readers are advised to seek out preffesional advice in the relevent feilds from licensed profesionals. This update is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. [ https://justpaste.it/ch2qt/pdf ]. Global Markets News Network is a commercial digital brand compensated to provide coverage of news and developments related to innovative companies as detailed in the full documentation and it is thus subject to conflicts of interest. Contact Details News Coverage ronald@futuremarketsresearch.com

September 19, 2024 07:45 AM Eastern Daylight Time

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Join Benchmark International's Exclusive Webinar "Seller Motivation: What Goes Into the Decision to Sell?"

Benchmark International

Are you considering selling your business? Deciding when and why to sell is one of the most significant decisions you’ll ever make as a business owner. While maximizing financial proceeds is often at the forefront of these decisions, it’s essential to recognize that it’s not the only factor. Life circumstances, time with family, and other qualitative considerations can often outweigh financial gain. To help you navigate this complex process, we invite you to join our upcoming webinar: Seller Motivation: What Goes Into The Decision To Sell? Space is filling up fast, so register today! Why You Should Register Selling a business is about more than just crunching the numbers. In this exclusive webinar, you’ll gain valuable insights into the full spectrum of motivations that drive business owners to sell. Understanding these motivations can help you make a well-rounded and informed decision about your business’s future. This webinar is a must-attend for business owners contemplating the sale of their business, particularly in today’s strong but disciplined market. By attending, you’ll be better equipped to evaluate both the financial and personal factors that play a crucial role in this life-changing decision. Whether you’re focused on securing a comfortable financial future or prioritizing time with loved ones, the information presented will help you weigh these considerations effectively. Spots are limited, so don’t miss this opportunity to secure your spot. What You’ll Learn This webinar offers actionable insights into the decision-making process for business owners. Here’s what you can expect to learn: The wide range of reasons why business owners choose to sell, beyond just financial incentives How personal life events, such as family needs and future aspirations, can influence your decision A look at the current M&A market and how buyers are approaching valuations How to balance personal and financial goals using the concept of indifference curves, which help weigh non-monetary values like time with family against financial returns By attending, you’ll gain the tools to make a decision that aligns with your long-term vision—both personally and financially. Spots Are Filling Fast – Register Now! If you’re ready to gain clarity on your motivations for selling and align your decision with both your personal and financial goals, this is the webinar for you. Don’t miss out—register now and take the first step toward making a well-informed, strategic decision about the future of your business. ABOUT BENCHMARK INTERNATIONAL: Benchmark International is a global M&A firm that provides business owners with creative, value-maximizing solutions for growing and exiting their businesses. Benchmark International has handled over $11 billion in transaction value across various industries from offices across the world. With decades of M&A experience, Benchmark International’s transaction teams have assisted business owners with achieving their objectives and ensuring the continued growth of their businesses. The firm has also been named the Investment Banking Firm of the Year by The M&A Advisor and the Global M&A Network as well as the #1 Sell-side Exclusive Privately-held M&A Advisor in the World by Pitchbook and Refinitiv's Global League Tables. Contact Details Brittney Zoeller +1 813-898-2350 zoeller@benchmarkintl.com Company Website https://www.benchmarkintl.com/

September 16, 2024 09:54 AM Eastern Daylight Time

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Comcast to Expand Fiber Broadband Services Across Northern California

Comcast California

Comcast announced it will expand its reliable, smart, high-speed, fiber broadband network in both residential and commercial neighborhoods in Northern California’s Marin and Sutter counties. By mid-2026 these expansion efforts will bring Comcast’s next-generation network to over 150 locations in Marin County and over 450 locations in Sutter County, both of which had previously been unserved. This broadband network expansion is made possible by a $14 million Federal Funding Account (FFA) Grant from the California Public Utilities Commission (CPUC) and private funding by Comcast. Comcast also recently announced it has received a $26 million FFA grant to expand its fiber-rich network in Tulare County, which will bring broadband services to nearly 6,200 unserved locations by early 2026. “At Comcast we understand that reliable, high-speed Internet has become a necessity to not only support those looking to participate in the ever-growing digital economy, but also to connect students, families and seniors to those moments that matter the most,” said David Tashjian, Regional Senior Vice President of Comcast California. “This continued investment of funds from the California Public Utilities Commission (CPUC) will allow us to expand into unserved communities throughout Marin and Sutter Counties, which will provide residents and businesses with a future of unlimited possibilities.” “This grant project will help level the playing field for a lot of families in Sutter County who have not previously had access to high-speed Internet,” said Mat Conant, Chair of the Sutter County Board of Supervisors. “This is really important for anyone doing any research for school or work, and for small business owners.” “There has always been an overwhelming demand to improve and expand our broadband services in Marin County,” said Eric Lucan of the Marin County Board of Supervisors. “That need is particularly important for our senior community, including my constituents within a mobile home community in Novato. I commend the California Public Utilities Commission (CPUC) and Comcast on today’s announcement and I’m excited to see the lasting impacts these awards will have in connecting more residents to high-speed Internet and the economic opportunities they will create.” Comcast’s commitment to new communities goes beyond network expansion efforts, addressing digital opportunities in communities through Project UP, the company’s $1 billion dollar commitment to help tens of millions of people connect to the Internet and build futures of unlimited possibilities. Over the past three years, Comcast has invested more than $130 million in cash and in-kind donations into California nonprofits focused on helping people build digital skills, expanding WiFi connected Lift Zones and funding connectivity and Internet adoption programs. Comcast’s funding also supports ongoing efforts to build awareness about affordable connectivity services like Internet Essentials, which offers eligible households high-speed Internet for $9.95/month or Internet Essentials Plus for $29.95/month. Affordable computers are also available through Internet Essentials. Since its inception in 2011, the program has connected more than 2.2 million Californians. Residential customers will be able to take advantage of Xfinity’s full suite of products, including Internet, video, mobile, voice and managed home solutions. For local businesses, Comcast Business will offer a suite of connectivity, communications, networking, cybersecurity, wireless, and managed solutions to help organizations of different sizes prepare for what’s next. Industry analysts and associations have consistently recognized Comcast Business as a leader and innovator, and one of the fastest-growing providers of Ethernet services. Comcast’s network and Internet experience are powering homes today and into the future. Ultimate Capacity: Xfinity customers connect more than 1 billion devices across the company’s network annually. With the next-generation Xfinity gateways, we deliver the most advanced WiFi technology carrying three times more bandwidth to power streaming, gaming, videoconferencing, and more, simultaneously. Fastest Internet: Nearly a third of Xfinity Internet customers subscribe to gigabit speed products. Recently Comcast connected the first customers in the world to a DOCSIS 4.0 connection, delivering symmetrical gig speeds over existing connections in customers’ homes with plans to continue to rollout these speeds across the country over the coming years. Unprecedented Coverage: The latest Xfinity Gateway provides a more reliable connection throughout the home. Customers can get wall-to-wall WiFi coverage with a powerful WiFi Boost Pod that extends coverage to hard-to-reach areas of the home. Most Reliable Connection: Comcast is scaling the nation’s largest and most reliable network that passes 62 million homes and businesses and counting. The company launched Storm-Ready WiFi, a new device that comes powered with cellular and battery backup to help keep customers connected even when the power goes out. Ultra-Low Latency: The Xfinity network and the latest Xfinity Gateway are a powerful combination that deliver ultra-low latency for those moments when response times matter most like video games, a fast-growing category with Xfinity households averaging more than one gaming console per home. For local businesses, Comcast Business will offer a suite of connectivity, communications, networking, cybersecurity, wireless, and managed solutions to help organizations of different sizes prepare for what’s next. Comcast Business has been consistently recognized by industry analysts and associations as a leader and innovator, and one of the fastest-growing providers of Ethernet services. ### About Comcast Business Comcast Business offers leading global businesses the technology solutions and forward-thinking partnership they need. With a full suite of solutions including fast, reliable connectivity, secure networking solutions and advanced cybersecurity and a range of managed service options, Comcast Business is ready to meet the needs of businesses of all sizes. Comcast Business has been recognized by leading analyst firms for its continued growth, innovation, and leadership, and is committed to partnering with customers to help them drive their businesses forward. For more information, call 800-501-6000. Follow @ComcastBusiness on social media networks at http://business.comcast.com/social. About Comcast Corporation Comcast Corporation (Nasdaq: CMCSA) is a global media and technology company. From the connectivity and platforms we provide, to the content and experiences we create, our businesses reach hundreds of millions of customers, viewers, and guests worldwide. We deliver world-class broadband, wireless, and video through Xfinity, Comcast Business, and Sky; produce, distribute, and stream leading entertainment, sports, and news through brands including NBC, Telemundo, Universal, Peacock, and Sky; and bring incredible theme parks and attractions to life through Universal Destinations & Experiences. Visit www.comcastcorporation.com for more information. Contact Details Comcast California Jon Koriel +1 925-315-2690 jon_koriel@comcast.com Company Website https://california.comcast.com/

September 12, 2024 01:46 PM Pacific Daylight Time

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Flash Transforms Parking at Denver International Airport

Flash

Flash, the leading end-to-end parking technology platform, announced today it has completed an overhaul of public and employee parking at Denver International Airport (DEN) through a contract the City and County of Denver awarded in August 2024. In just 22 days, Flash deployed its platform across the airport’s nine public and employee parking garages and lots, bringing a state-of-the-art parking experience to DEN’s 40,000 employees and the 77.8 million passengers they serve annually. "Flash’s commitment to DEN has been tremendous and we look forward to a bright future that provides innovative solutions to improve the customer experience," said Mark Nagel, Senior Vice President of Parking and Commercial Transportation, Denver International Airport. In its first few weeks of deployment, DEN reports improved traffic flow and reduced wait times for vehicles entering and exiting the airport’s parking facilities. DEN’s deployment of Flash’s platform spans 144 lanes and features 137 kiosks, 97 license plate recognition (LPR) lanes, and 49 automatic vehicle identification (AVI) lanes. With the new AVI lanes, employees can enter and exit automatically in seconds via vehicle-mounted passes that require no interaction with their phones or kiosks. “DEN is the sixth busiest airport in the world and sees millions of parking transactions each year, requiring the highest service level,” said Flash CEO Dan Sharplin. “Our technology breadth and industry-leading scale, plus our maniacal focus on the driver experience, made us confident we could support DEN’s traffic volumes and service levels while getting passengers and employees through parking transactions quickly, and it’s hugely gratifying to see it live.” DEN also benefits from the Flash platform’s design as an enhanced cloud-based parking solution. In the event of an internet, payment processor, network or cloud disruption, the platform maintains continuous operations and critical payment processing capabilities so the airport’s parking facilities stay up and running. About Flash Flash is a pioneering technology company bringing seamless parking and EV charging experiences to drivers through a first-of-its-kind digital ecosystem. Flash’s platform connects reservable parking and charging in the apps drivers use every day with garage, surface lot, event, and valet parking locations—connected and controlled via a cloud-based operating system with unrivaled intelligence. Customer-obsessed brands partner with Flash to deliver digital, easy-to-use, reliable, and increasingly frictionless experiences to drivers eager to pay for a solution that eliminates wasted time, excess emissions, and stress. The solution has arrived.. Visit www.flashparking.com to learn more. Contact Details Ray Young +1 512-694-6097 ray@razorsharppr.com Company Website https://www.flashparking.com/

September 12, 2024 09:00 AM Central Daylight Time

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Flash Secures $85 Million to Back Special Purpose Vehicle to Propel Growth and Provide Flexible Payment Options

Flash

Flash, the industry-leading end-to-end parking technology platform, today announced that it has closed on $85 million in debt financing for a newly formed special purpose vehicle (“SPV”) to accelerate platform adoption and offer Flash clients an expanded range of flexible payment options. The debt capital, which can be increased up to $100 million, was provided by Vantage Infrastructure (“Vantage”), a leading independent specialist infrastructure credit fund. “Asset owners and operators have a myriad of budgetary and deployment preferences – the payment options we can now extend through the SPV will allow customers to join the Flash platform on terms that work best for them," said Chris Donus, President of Flash. “Innovation in payment options is as critical as platform innovation in pursuit of our vision for the parking industry’s transformation in light of the scale and momentum we're on pace to achieve." Flash’s payment options allow clients to select amongst flexible monthly payment plans that suit their budgets, regardless of scale, asset type, or configuration. This includes EV charging infrastructure and other advanced parking technologies offered by Flash. Flash anticipates extending the SPV structure and partnership with Vantage in future financings. ”We’re pleased to support Flash with a tailored financing solution that enables their team to continue to meet and exceed their clients’ need for better transport related infrastructure,” said Nick Cleary, Senior Partner at Vantage. “This is a great example of the opportunity to upgrade and transform proven traditional infrastructure that saves time and costs for drivers and help build out the EV charging network.” Evercore acted as Flash’s exclusive financial advisor, and Cadwalader, Wickersham & Taft LLP provided legal counsel to Flash. Steptoe LLP acted as counsel to Vantage. About Flash Flash is a pioneering technology company bringing seamless parking and EV charging experiences to drivers through a first-of-its-kind digital ecosystem. Flash’s platform connects reservable parking and charging in the apps drivers use every day with garage, surface lot, event, and valet parking locations — connected and controlled via a cloud-based operating system with unrivaled intelligence. Customer-obsessed brands partner with Flash to deliver digital, easy-to-use, reliable, and increasingly frictionless experiences to drivers eager to pay for a solution that eliminates wasted time, excess emissions, and stress from driving. The solution has arrived. Visit www.flashparking.com to learn more. About Vantage Infrastructure Vantage Infrastructure is an independent infrastructure specialist manager committed to delivering sustainable investment solutions with an equity and debt infrastructure investment portfolio of over US $4 billion invested in infrastructure assets across Europe, North America, and Australia on behalf of global clients. Contact Details Razor Sharp PR Ray Young +1 512-694-6097 ray@razorsharppr.com Company Website https://www.flashparking.com/

September 09, 2024 09:00 AM Central Daylight Time

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Introducing Brick Media: A New Force in Media Management and Innovation

Full Scope PR

Brick Media announces its powerful entrance into the media landscape, asserting itself as a catalyst for transformation. With a bold vision for content innovation and unparalleled management expertise, Brick Media is set to redefine and lead the charge in shaping the future of media. As a full-service media management firm at the intersection of content strategy and business execution, Brick Media is committed to nurturing the growth and monetization of its clients' careers across the digital media landscape. With a multifaceted approach, the company aims to elevate brands and voices across sports, entertainment, and beyond. Drawing from over a decade of unparalleled success in sports and entertainment management, Aaron & André Eanes of A&A Management bring their strategic expertise and deep industry insights to position Brick Media as a transformative force in the media sector. Leading this ambitious venture alongside them is CEO of Brick Media, Maggie Clifton. Formerly with Blue Wire and Wasserman, Maggie brings a wealth of experience and a visionary outlook to the company. Under her guidance, a team of highly skilled media professionals will spearhead the optimization of innovative and compelling content. Together, they stand ready to redefine the boundaries of the industry, heralding a new era of influence. "We founded Brick Media with the strategic vision of being a vital resource in the media industry for those seeking to elevate their clients' success to new levels. When we helped with the launch of New Heights, it revealed a critical need for an independent partner adept at steering through the intricacies of advertising, ancillary revenue streams, digital creation, and social growth. Brick Media fulfills that role, offering expert guidance and the best-in-class resources to empower achieving maximum value." says Aaron & Andre Eanes of A&A Management Group. "Brick Media is here to support our partners’ media businesses via strategy, monetization, distribution, marketing, and all other opportunities for growth. We’ve been building quietly all year and are excited to finally launch publicly.” says CEO of Brick Media, Maggie Clifton. In a remarkable inaugural achievement, Aaron Eanes of A&A Management Group and Maggie Clifton of Brick Media led negotiations a ground-breaking deal between the leading podcast studio Wondery and the widely acclaimed show, "New Heights with Jason and Travis Kelce," alongside Andre Eanes of A&A Management Group and Jason Bernstein of Clarity Football. This marks the beginning of Brick Media's mission to forge impactful partnerships and deliver unparalleled growth across the digital media landscape. Brick Media is dedicated to pushing the boundaries of creativity and strategic content development. As the company continues to forge influential partnerships and manage transformative projects, Brick Media is poised to become a leader in the digital media ecosystem. About Brick Media Brick Media is a media management firm specializing in content strategy and business development. Dedicated to fostering client growth and monetization across diverse media landscapes, including sports, entertainment, and news, Brick Media is set to make its mark on the future of media. Contact Details Alessandra Chisolm alessandra@fullscopepr.com

September 05, 2024 09:00 AM Eastern Daylight Time

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Join Travis Kelce for the Second Annual "Kelce Car Jam" - A Celebration of Cars, Community, and Youth Empowerment.

Full Scope PR

Gear up for an exhilarating evening filled with cars, community, and camaraderie at the 2nd Annual Kelce Car Jam taking place on Saturday, October 5, 2024, from 5-8pm CT. This year’s event, held on Walnut Street in downtown Kansas City, promises to be a thrilling block party that perfectly sets the stage for the Chiefs' Monday Night Football game. Join three-time Super Bowl champion Travis Kelce and his Kansas City Chief teammates as they showcase some of the city’s coolest vintage and luxury cars, including select vehicles from their personal collections. This vibrant event is not just a car show; it's a celebration of community spirit, designed to bring together fans from all walks of life. Adding to the excitement, the talented kids from Operation Breakthrough Ignition Lab will be joining us to show off some of their automotive work. Operation Breakthrough's Ignition Lab is a state-of-the-art STEM workspace that Travis Kelce helped open and has significantly supported. This lab is designed to provide real-world learning opportunities in STEM for high school students, preparing them for future careers and life. They'll present their impressive automotive projects and offer a taste of culinary delight from their newly refurbished food truck. This initiative, supported by the Eighty-Seven & Running Foundation, underscores Travis Kelce’s commitment to empowering youth through education and opportunity. The Kelce Car Jam offers fun for all ages with a variety of food, drinks, and activities from our partners: Raising Cane’s Chicken Fingers, Travis Kelce’s Kitchen BBQ and Andy’s Frozen Custard. Attendees can choose between two ticket levels: General Admission or VIP. The VIP experience includes intimate access to an exclusive indoor space, complete with food and drinks. Tickets will go on sale starting Wednesday, September 4th and can be purchased at 87running.org. Don’t miss out on this unique opportunity to experience the magic of Kelce Car Jam, where the love for cars meets the heart of the community. Secure your tickets now and be part of a night to remember! About Eighty-Seven & Running The Eighty-Seven & Running Foundation is dedicated to empowering Kansas City's youth by providing vital resources and support to those who are undeserved and vulnerable. The foundation is committed to fostering community, encouraging personal growth, and paving a path to success for these young individuals. Contact Details Full Scope PR Team Travis Kelce tk@fullscopepr.com Eighty-Seven & Running Foundation Info info@87running.org Company Website https://87running.org/

September 04, 2024 07:00 AM Central Daylight Time

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